Effect of denaturants on the speciation of amino acid complexes-Computer augmented modelling studies - IV: Cobalt(II), copper(II) and zinc(II) complexes of L-glutamic acid in water-N,N' -dimethylformamide mixtures^†

Abstract

A computer assisted investigation has been made on the nature of complexes of cobalt(Il), copper(II) and zinc(II) with L-glutamic acid. The distribution of these metal ions amongst the complexes formed with the above amino acid has been computed. The formation constants required for this calculation have been determined experimentally by monitoring H⁺ concentration. The formation constants have been refined with the computer program, MINIQUAD 75ᵒ using the primary alkalimetric data. The predominant complexes formed are CoL, CoL<img src='http://www.niscair.res.in/jinfo/twobytwo.gif' border=0>. CuL<img src='http://www.niscair.res.in/jinfo/doubletwo.gif' border=0>, CuL,CuLH⁺.CuL²H^-.ZnL,ZnL<img src='http://www.niscair.res.in/jinfo/doubletwo.gif' border=0>.and ZnLH⁺. The distribution patterns of different species varies with the relative concentrations of the metal ion and the ligand.