Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/40522| Title: | Synthesis of 9-aryl-6-(4-trifluoromethylphenyl)-1,2,4-triazolo[4,3-a] [1,8]naphthyridines using Cu(OAc)2 under microwave irradiation and their antibacterial activity |
| Authors: | Mogilaiah, K Kumar, K Shiva Rao, A Nageswara Babu, H Ramesh |
| Keywords: | 1,2,4-Triazole;1,8-naphthyridine;Cu(OAc)2;Microwave irradiation;Antibacterial activity |
| Issue Date: | Feb-2017 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | An effective, practical and simple approach towards the synthesis of 9-aryl-6-(4-trifluoromethylphenyl)-1,2,4-triazolo [4,3-a]-[1,8]naphthyridines 8 from the corresponding aryl aldehyde 3-(4-trifluoromethylphenyl)-1,8-naphthyridin-2-ylhydrazones 7 has been achieved, using Cu(OAc)2 in combination with microwave irradiation. The products are obtained in good yields and in a state of high purity. The structural assignments of compounds 3-8 are based on their elemental analyses and spectral (IR, 1H NMR and mass spectroscopy) data. The compounds 8 have been screened for their antibacterial activity. |
| Page(s): | 171-176 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.56B(02) [February 2017] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 56B(2) 171-176.pdf | 72.83 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.