Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/41412
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dc.contributor.authorSharma, R K-
dc.contributor.authorJoseph, Sherly-
dc.date.accessioned2017-04-24T06:58:28Z-
dc.date.available2017-04-24T06:58:28Z-
dc.date.issued1996-08-
dc.identifier.issn0975-0975(Online); 0376-4710(Print)-
dc.identifier.urihttp://nopr.niscair.res.in/handle/123456789/41412-
dc.description639-642en_US
dc.description.abstractFormation and proton association constants have been determined using BEST and PKAS programs. Species distributions are plotted using program BEST in order to see the presence of M-tetracycline species in biological fluids. Formation constants and species distribution curves indicate the strong interaction of Ca, Mg, Cu, Ni, Co and Fe with tetracycline and the predominant species at biological pH value is of MHL type. Action of tetracycline is explained on the basis of strong chelation behaviour with Mg. Molecular mechanics calculations show that the chelating sites are 010-011 for Cu-tetracycline complex.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-A Vol.35A(08) [August 1996]en_US
dc.titleFormation constants and molecular modelling studies of metal ion-tetracycline complexesen_US
dc.typeArticleen_US
Appears in Collections:IJC-A Vol.35A(08) [August 1996]

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