Oxidation of uronic acids by sodium N-chloro-<i>p</i>-toluenesulphonamide in alkaline medium : A kinetic study

Abstract

Kinetics of oxidation of <img src='http://www.niscair.res.in/jinfo/smaller.gif' border=0>-glucuronic acid and <img src='http://www.niscair.res.in/jinfo/smaller.gif' border=0>-galacturonic acid (S) by sodium N-chloro-<i>p</i>-toluenesulphonamide or chloramine-T (CAT) in the presence of alkali at 35° has been investigated and the rate= <i>k </i> [CAT][S][HO^­]. The product, <i>p</i>-toluenesulphonamide has no influence. Increase in ionic strength increases the rate and the rate decreases when the dielectric constant of the medium is decreased. The rate increases in D₂O medium. Activation parameters have been determined from the Arrhenius plots. The mechanism involves the formation of an enediol anion followed by its oxidation by the positive halogen in a rate limiting step.