Effect of <em>Burahol </em>[<em>Stelechocarpus burahol </em>(Blume) Hook.f. & Thomson] fruits extract mouthwash on mouth bad deodorization

Abstract

<em>Burahol </em>[<em>Stelechocarpus burahol </em>(Blume) Hook.f. &amp; Thomson] fruit is well known as food and used traditionally as bad deodorization. The objective of this study was to examine mouth bad deodorization activity of <em>burahol</em> mouthwash. Firstly, methyl mercaptan capturing activity of the <em>burahol</em> fruit extracts was evaluated using gas chromatography. The antibacterial activity against <em>Porphyromonas ginggivalis, </em>a volatile sulfide compound (VSC)-producing Gram-negative anaerobic bacterium was tested. The mouthwash mouth bad deodorization activity was performed with cross over design in healthy subjects, randomized controlled trial. Subjects were treated by the <em>burahol </em>mouth wash, as positive control was used commercial mouth wash containing green tea extract. The <em>burahol</em> fruits extract captured 97.5% methyl mercaptan. The <em>burahol </em>mouthwash demonstrated no antibacterial activity against <em>P. ginggivalis. </em>The treatment of the <em>burahol </em>mouthwash on the subjects reduced the volatile sulfur compounds (VSCs) concentration. The <em>burahol</em> mouthwash mouth bad deodorization activity is not different statistically compared with that positive control (P &lt; 0.05). This study showed that <em>S. burahol </em>fruits demonstrated the mouth bad odor reducing activity.