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http://nopr.niscpr.res.in/handle/123456789/42220| Title: | Green synthesis, antibacterial and anti-inflammatory activities of 2-(2-substituted[1,8]naphthyridin-3-yl)-5-(substituted-2-thienyl)-1,3,4-oxadiazoles |
| Authors: | Mogilaiah, K Venkanna, Ch Rao, A Nageswara Babu, H Ramesh |
| Keywords: | 1,8-Naphthyridines;1,3,4-oxadiazoles;Iodobenzene diacetate[ PhI(OAc)2] solid state;Antibacterial activity;Anti-inflammatory activity |
| Issue Date: | Jun-2017 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | An efficient and mild method for the synthesis of 2-(2-substituted[1,8]naphthyridin-3-yl)-5-(substituted-2-thienyl)-1,3,4-oxadiazoles 4 is reported by the oxidation of the corresponding Nʹ3-[1-(substituted-2-thienyl)methylidene]-2-sustituted[1,8]naphthyridine-3-carbohydrazides 3 with iodobenzene diacetate(PhI(OAc)2] in solid state. The reaction proceeds efficiently giving the products in good yields and excellent purities. The structural assignments of compounds 3 and 4 are based on their elemental analyses andspectral (IR, 1H NMR and MS) data. The compounds 4 have been screened for their antibacterial and anti-inflammatory activities. |
| Page(s): | 670-676 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.56B(06) [June 2017] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 56B(6) 670-676.pdf | 131.14 kB | Adobe PDF | View/Open |
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