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Title: Aphrodisiac efficacy of Blepharis sindica seeds: A comparative assessment using different solvent types
Authors: Vyas, Govind
Mathur, Manish
Patel, Nikunjana A
Patel, R P
Keywords: Alkaloid;Male infertility;Prostate;Solvent extraction;Steroidal sapogenin;Testosterone
Issue Date: Oct-2017
Publisher: NISCAIR-CSIR, India
Abstract: Sexual dysfunction, particularly male infertility has long been identified, discussed and documented in ancient literature worldwide. Now, this syndrome has been well established by the civilizing process of a human being extravagant with a sedentary lifestyle, environmental factors and changing food habits. In the present study aphrodisiac properties of Blepharis sindica seeds were clinically evaluated with quantitative evaluation of bioactive molecules, and with some biological, physical, behaviour (Psychological) and biochemical parameters. These parameters were evaluated with different solvents viz., ethanol, hydroalcholic and acetone. The concentration of steroidal sapogenin and alkaloid were recorded higher with ethanol compared to two other solvents. Extracts showed positive impacts of the drug on sex organ weight (seminal vesicle, prostate, epididymis, and Vas-deferens), sexual behavior parameters (higher mount and intromission frequency; lesser mount latency, intromission latency and post- ejaculatory interval) and testosterone levels in treated animals. By and large, our outcomes have uncovered that the ethanol concentrate of B. sindica seeds could be utilized as a stimulator of sexual conduct in male rats. The sexual enhancer impact of the plant extract may be because of the vicinity of alkaloids and steroidal sapogenin with activation of certain hormones and neurotransmitters.
Page(s): 223-230
ISSN: 0975-0959 (Online); 0301-1208 (Print)
Appears in Collections:IJBB Vol.54(5) [October 2017]

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