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http://nopr.niscpr.res.in/handle/123456789/43807| Title: | Autocatalysis in the oxidation of, ɑ-aminoacids |
| Authors: | Ramachandran, M S Easwaramoorthy, D Raj, R P Malim Mani Vivekanandam, T S |
| Issue Date: | Apr-1993 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The oxidative decarboxylation of eleven ɑ-amino acids (AA) by N-bromoacetamide (NBA) are studied. The integrated first order equation for the disappearance of NBA shows curvature towards time axis even at the early stages of the reaction while the plots [NBA]t versus time are linear even upto 75% conversion of the oxidant. The rate equation obeys - d[NBA]/dt = (ka[AA] + kb) [NBA] The influence of [OH-] on kobs is observed in glycine, alanine and to a smaller extent in serine and thre-onine. The kinetic scheme involves the formation of a complex intermediate between N-bromoacetamide and amino acid anion which then decomposes in the rate limiting step. The absorption spectrum of the reaction mixture shows the formation of imine as the intermediate Which may catalyses the reaction. |
| Page(s): | 332-337 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.32A(04) [April 1993] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 32A(4) 332-337.pdf | 460.91 kB | Adobe PDF | View/Open |
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