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http://nopr.niscpr.res.in/handle/123456789/44182| Title: | Formation of esters and amides via metal-free Csp2-Csp3 bond cleavage of α-nitro ketone: Mechanistic insight to the reaction pathway |
| Authors: | Sarma, Manas Jyoti Phukan, Prodeep |
| Keywords: | C-C Cleavage;α-nitroketone;Esters;Amide;Bromamine-T |
| Issue Date: | Apr-2018 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A catalyst free protocol for nucleophilic Csp2-Csp3 bond cleavage of α-nitroketone has been achieved for the formation of C-O and C-N bond. A series of differently substituted α-nitroketones could be selectively cleaved and converted into corresponding esters and tosylamides in presence of alcohols and bromamine-T respectively. Mechanism of the C-C bond cleavage has been proposed by identifying different reaction intermediates using IR and NMR spectroscopic methods. |
| Page(s): | 523-533 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.57B(04) [April 2018] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 57B(4) 523-533.pdf | 417.88 kB | Adobe PDF | View/Open |
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