Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/4440Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kuhad, Anurag | - |
| dc.contributor.author | Chopra, Kanwaljit | - |
| dc.date.accessioned | 2009-06-03T11:50:01Z | - |
| dc.date.available | 2009-06-03T11:50:01Z | - |
| dc.date.issued | 2008-02 | - |
| dc.identifier.issn | 0019-5189 | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/4440 | - |
| dc.description | 108-111 | en_US |
| dc.description.abstract | Peripheral neuropathy is one of the common complications of diabetes mellitus. It is frequently associated with debilitating pain. The present study was designed to investigate effect of Lycopene, a carotenoid found in tomatoes, on hyperalgesia and cold allodynia in streptozotocin (STZ) induced diabetic rats. After 4-weeks of STZ injection, diabetic mice exhibited a significant thermal hyperalgesia cold allodynia, hyperglycemia and loss of body weights as compared with control rats. Chronic treatment of lycopene for 4 weeks significantly attenuated the cold allodynia and thermal hyperalgesia. The results emphasize the role of antioxidant such as lycopene as an adjuvant therapy in the treatment of diabetic neuropathy. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | CSIR | en_US |
| dc.source | IJEB Vol.46(02) [February 2008] | en_US |
| dc.subject | Diabetic neuropathy | en_US |
| dc.subject | Hyperalgesia | en_US |
| dc.subject | Lycopene | en_US |
| dc.subject | Oxidative stress | en_US |
| dc.title | Lycopene ameliorates thermal hyperalgesia and cold allodynia in STZ-induced diabetic rat | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJEB Vol.46(02) [February 2008] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 46(2) 108-111.pdf | 152.83 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.