<i style="">In vitro</i> antiviral activity of plant extracts on goatpox virus replication

Abstract

Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication <i style="">in vitro</i>. Of the 4 plants, extract of <i style="">Acacia arabica</i> (Babul) and<i style=""> Eugenia jambolana </i>(Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93±0.38 and 1999.73±0.50 mg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of <i style="">Acacia arabica</i> and <i style="">Eugenia jambolana</i> leaves inhibited GTPV replication <i style="">in vitro</i>.