Synthesis leading to novel 2,4,6-trisubstituted quinazoline derivatives, their antibacterial and cytotoxic activity against THP-1, HL-60 and A375 cell lines

Chandrika, P Mani; Yakaiah, T; Narsaiah, B; Sridhar, V; Venugopal, G; Rao, J Venkateshwara; Kumar, K Pranay; Murthy, U S N; Rao, A Raghu Ram

Welcome to NIScPR Online Periodicals Repository

You can now access full text articles from research journals published by CSIR-NIScPR! Full text facility is provided for all nineteen research journals viz. ALIS, AIR, BVAAP, IJBB, IJBT, IJCA, IJCB, IJCT, IJEB, IJEMS, IJFTR, IJMS, IJNPR, IJPAP, IJRSP, IJTK, JIPR, JSIR & JST. NOPR also hosts three Popular Science Magazines viz. Science Reporter (SR), Vigyan Pragati (VP) & Science Ki Duniya (SKD) and a Natural Products Repository (NPARR).

Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/4549

Full metadata record

DC Field	Value	Language
dc.contributor.author	Chandrika, P Mani	-
dc.contributor.author	Yakaiah, T	-
dc.contributor.author	Narsaiah, B	-
dc.contributor.author	Sridhar, V	-
dc.contributor.author	Venugopal, G	-
dc.contributor.author	Rao, J Venkateshwara	-
dc.contributor.author	Kumar, K Pranay	-
dc.contributor.author	Murthy, U S N	-
dc.contributor.author	Rao, A Raghu Ram	-
dc.date.accessioned	2009-06-09T11:52:56Z	-
dc.date.available	2009-06-09T11:52:56Z	-
dc.date.issued	2009-06	-
dc.identifier.issn	0376-4699	-
dc.identifier.uri	http://hdl.handle.net/123456789/4549	-
dc.description	840-847	en_US
dc.description.abstract	A series of novel 2,4,6-trisubstituted quinazoline derivatives 6 have been synthesized from anthranilic acids 1 in five steps via benzoxazinones 2, N-benzoyl benzamides 3, quinazol-4-ones 4, 4-chloroquinazolines 5. Products 6 have been screened for antibacterial and cytotoxic activity, promising compounds have been identified.	en_US
dc.language.iso	en_US	en_US
dc.publisher	CSIR	en_US
dc.source	IJC-B Vol.48B(06) [June 2009]	en_US
dc.subject	Benzoylation	en_US
dc.subject	acylation	en_US
dc.subject	cyclisation	en_US
dc.subject	quinazolones	en_US
dc.subject	quinazolines	en_US
dc.title	Synthesis leading to novel 2,4,6-trisubstituted quinazoline derivatives, their antibacterial and cytotoxic activity against THP-1, HL-60 and A375 cell lines	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-B Vol.48B(06) [June 2009]

Files in This Item:

File	Description	Size	Format
IJCB 48B(6) 840-847.pdf		203.36 kB	Adobe PDF	View/Open

Show simple item record