Comparative analysis of the biochemical parameters among the three Prakriti individuals having Type 2 diabetes mellitus

Abstract

The occurrence of multi-organ affecting <em>Type 2</em> diabetes mellitus is increasing day by day that consequently becomes a serious threat to public health. According to Ayurveda, individual’s basic constitution (<em>Prakriti</em>) describes its predisposition and prognosis to disease status and also the treatment for disease but no detailed studies carried out yet on diabetic individuals of three <em>Prakriti</em> groups on biochemical aspects. This study was conducted with twelve patients in each three <em>Prakriti</em> groups having <em>Type 2</em> diabetes mellitus to determine the differences of some anthropometrical and biochemical parameters amongst them. Clinical profiling and various biochemical parameters of liver and kidney, lipid profiles and anti-oxidant enzymes were assayed. Significant differences were observed amongst the subjects belonging in different <em>Prakriti</em> groups. Differences in liver function enzymes and kidney function parameters and lipid profiles revealed that the subjects of <em>Kapha</em> and <em>Pitta</em> <em>Prakriti</em> were predominant groups. Glycosylated haemoglobin percentage was higher in <em>Pitta</em> <em>Prakriti</em> individuals. The screening process of the study indicated that diabetic individuals mostly belong to the <em>Pitta</em> and <em>Kapha</em> <em>Prakriti</em> groups of which <em>Kapha</em> <em>Prakriti</em> was more prone to hepatic and renal disorder and <em>Pitta</em> <em>Prakriti</em> was more susceptible towards cardiac disorder due to their diabetic complications.