Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/49702
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKarthick, V.-
dc.contributor.authorAkhila, C.-
dc.contributor.authorKumar, V. Ganesh-
dc.contributor.authorSubashini, D.-
dc.contributor.authorDhas, T. Stalin-
dc.contributor.authorGovindaraju, K.-
dc.contributor.authorVasanth, K.-
dc.date.accessioned2019-08-09T06:29:50Z-
dc.date.available2019-08-09T06:29:50Z-
dc.date.issued2019-08-
dc.identifier.issn0975-1033 (Online); 0379-5136 (Print)-
dc.identifier.urihttp://nopr.niscair.res.in/handle/123456789/49702-
dc.description1267-1273en_US
dc.description.abstractSeaweed polysaccharides are compounds with promising chemopreventive and chemotherapeutic activities. In this study, polysaccharides isolated from Sargassum seaweeds were tested for their efficiency in cancer therapy. Polysaccharides were isolated, purified, and characterized using nuclear magnetic resonance (NMR); and Fourier transform infrared (FT-IR) spectroscopic and matrix-assisted laser desorption ionization mass spectrometric (MALDI-MS). It was found that the polysaccharides from Sargassum sp. branches are sulfated galactose–fucose disaccharides and sulfated galactose monosaccharides attached to the main chain through (1–4) linkages. Further, the polysaccharides were tested for cytotoxicity and anticancer activity against human breast adenocarcinoma cell line (MCF-7) using the Annexin-V/propidium iodide (PI) staining method.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJMS Vol.48(08) [August 2019]en_US
dc.subjectPolysaccharidesen_US
dc.subjectSpectroscopyen_US
dc.subjectApoptosisen_US
dc.subjectSargassum sp.en_US
dc.subjectAdenocarcinomaen_US
dc.titleIn vitro anticancer activity of Sargassum sp. polysaccharides against MCF-7 cell linesen_US
dc.typeArticleen_US
Appears in Collections:IJMS Vol.48(08) [August 2019]

Files in This Item:
File Description SizeFormat 
IJMS 48(8) 1267-1273.pdf415.3 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.