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|Title:||Effect of alpha-tocopherol supplementation on renal oxidative stress and Na+/K+-adenosine triphosphatase in ethanol treated Wistar rats|
Vasudevan, D M
|Keywords:||Alpha-tocopherol;Ethanol;Kidney;Oxidative stress;Na+ / K+-ATPase|
|Abstract:||Ethanol intoxication resulted in high extent of lipid peroxidation, and reduction in antioxidant defenses (decreased GSH, GSH/GSSG ratio, and catalase, SOD and GPx activities) and (Na+/K+)-ATPase activity in kidney. Alpha-tocopherol treatment effectively protected kidney from ethanol induced oxidative challenge and improved renal (Na+/K+)-ATPase activity. Ethanol induced oxidative stress in the kidney and decreased (Na+/K+)-ATPase activity could be reversed by treatment with ascorbic acid.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:||IJEB Vol.47(07) [July 2009]|
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