Synthesis and Electrochemical Analysis of Biologically Active Novel NiIIHMTAA and CuIIHMTAA Complexes

Abstract

Ni^IIHMTAA-14 and Cu^IIHMTAA-14 (HMTAA-14 = dichloro[2,4,9,13,15,20-hexamethyldibenzo-1,4,8,11-tetraazacyclotetradecatetraene]) macrocyclic complexes have been synthesized by template method and characterized by multiple characterization techniques. Electrochemical studies of Ni^IIHMTAA-14 and Cu^IIHMTAA-14 macrocyclic complexes carried out on Pt disc (tip-06.1204.120.) electrode (2 mm diameter) in methanol, DMSO and acetonitrile by employing cyclic voltammetry revealing that these macrocycles undergo one-electron electrochemical processes to form stable Ni(HMTAA)⁰ and Cu(HMTAA)⁺ species. Preliminary investigation of antimicrobial activities of these novel macrocyclic complexes has also been studied.