Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/5413
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dc.contributor.authorHegde, Karunakar-
dc.contributor.authorJoshi, Arun B-
dc.date.accessioned2009-07-21T11:33:31Z-
dc.date.available2009-07-21T11:33:31Z-
dc.date.issued2009-08-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/5413-
dc.description660-667en_US
dc.description.abstractOral pre-treatment with ethanolic extract of the roots of C. carandas (ERCC; 100, 200 and 400 mg/kg, po) showed significant hepatoprotective activity against CCl4 and paracetamol induced hepatotoxicity by decreasing the activities of serum marker enzymes, bilirubin and lipid peroxidation, and significant increase in the levels of uric acid, glutathione, super oxide dismutase, catalase and protein in a dose dependent manner, which was confirmed by the decrease in the total weight of the liver and histopathological examination. Data also showed that ERCC possessed strong antioxidant activity, which may probably lead to the promising hepatoprotective activities of C. carandas root extract. These findings therefore supported the traditional belief on hepatoprotective effect of the roots of C. carandas.en_US
dc.language.isoen_USen_US
dc.publisherCSIRen_US
dc.sourceIJEB Vol.47(08) [August 2009]en_US
dc.subjectAntioxidantsen_US
dc.subjectCarissa carandasen_US
dc.subjectCCl4en_US
dc.subjectHepatoprotective activityen_US
dc.subjectOxidative stressen_US
dc.subjectParacetamolen_US
dc.titleHepatoprotective effect of Carissa carandas Linn root extract against CCl4 and paracetamol induced hepatic oxidative stressen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.47(08) [August 2009]

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