Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells

Abstract

In the present study, the antioxidant, antimicrobial potential and antiproliferative activity of <em>Lactifluus rugatus</em> mushroom were determined. Thus, extracts of the mushroom were obtained using a Soxhlet device. Antioxidant and oxidant potentials were determined using Rel Assay kits. Antimicrobial potential was tested on 9 microorganisms using the modified agar dilution method. MTT test was conducted on A549 cells to determine the anti-proliferative activity. As a result, high level of antioxidant activity was determined in <em>L. rugatus</em>. Furthermore, it was determined that the mushroom had antimicrobial properties on tested bacteria and fungi and strong anti-proliferative activity on A549 cells. In conclusion, it was considered that <em>L. rugatus</em> had pharmacological potential and it can be utilized as a natural pharmacological agent.