Synthesis of fluorinated 3-hydrazino-1,2,4-triazino[5,6-b] indoles as novel herbicidal systems

Abstract

A few fluorinated 3-hydrazino-1,2,4-triazino[5,6-b] indoles (<strong>5</strong>-<strong>8</strong>) have been synthesized and screened for their herbicidal effect. Treatment of 3-hydrazino-8H/8-fluoro-1,2,4-triazino[5,6-b] indoles (<strong>3</strong> and <strong>4</strong>) with fluorinated acyl derivatives (<strong>A</strong> and <strong>B</strong>) yielded the rich fluorine 1,2,4-triazino indole. Structure of the products have been established by elemental analysis and spectral measurements. The presence and position of fluorine atoms have been deduced from ¹⁹F&nbsp;NMR. The novel fluorinated hydrazino-1,2,4-triazino[5,6-b] indoles have been tested for post-emergent herbicidal activity against grass weed species and broadleaf weed species.