Synthesis of copper oxide nanoparticles using leaf extract of Simaroubaglauca and its antibacterial study

Abstract

The present study is aimed at synthesizing extract CuO NPs using <em>Simaroubaglauca</em> plant by green synthesis method. The synthesized CuO NPs have been characterized by XRD, FTIR, SEM, EDAX and HR TEM techniques. XRD analysis showed that the particles are crystalline and monoclinic in nature. The average size of the particle is 31.1 nm. SEM images indicate that the particles area almost spherical in nature with some agglomeration. EDAX analysis and HRTEM confirmed the formation of CuO NPs. FTIR results indicated the presence of phytochemicals present in the plant extract, which is responsible for the formation of CuO NPs. Further, the antibacterial study of CuO NPs against four human pathogenic bacteria namely <em>Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis </em>and<em> Staphylococcus aureus</em> is carried out. The study showed that CuO NPs have significant antibacterial property against these human pathogenic bacteria.