Design and fabrication of hydrogel incorporated with copper nanoparticles loaded microsponge for antimicrobial and antioxidant activity

Abstract

A hydrogel has been designed as an antimicrobial agent with low toxicity and reduced side effects. The hydrogel has been fabricated with green synthesised copper nanoparticles loaded microsponges. Here, the copper nanoparticles have been synthesised from the leaf extract of Ocimum Sanctum. This fabricated hydrogel is checked for its pH and particle size by particle size analyser (PSA). The best hydrogel is assessed through resazurin microtitre assay for its antimicrobial activity. Using DPPH assay, it is also checked for its antioxidant activity. The results show that the fabricated hydrogel incorporated with copper nanoparticles loaded microsponge act as an excellent antimicrobial gel and has shown good antioxidant potential.