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http://nopr.niscpr.res.in/handle/123456789/59817Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ganesh, N S | - |
| dc.contributor.author | Spandana, K V L D | - |
| dc.contributor.author | Narsaiah, A Venkat | - |
| dc.date.accessioned | 2022-05-31T06:56:39Z | - |
| dc.date.available | 2022-05-31T06:56:39Z | - |
| dc.date.issued | 2022-05 | - |
| dc.identifier.issn | 2583-1321 (Online); 0019-5103 (Print) | - |
| dc.identifier.uri | http://nopr.niscpr.res.in/handle/123456789/59817 | - |
| dc.description | 503-507 | en_US |
| dc.description.abstract | A simple and efficient route has been developed for enantioselective synthesis of hyperparathyroidism agent (R)-Cinacalcet. The synthesis started from commercially available triflouromethyl benzaldehyde and 1-(naphthalen-1-yl) ethanone and completed in 8 steps with an overall yield 18.5%. The key reactions involved are Corey-Bakshi-Shibata chiral reduction and reductive amination. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | NIScPR-CSIR, India | en_US |
| dc.source | IJC Vol.61(05) [May 2022] | en_US |
| dc.subject | Wittig reaction | en_US |
| dc.subject | CBS-reduction | en_US |
| dc.subject | oxidation | en_US |
| dc.subject | reductive amination | en_US |
| dc.subject | hyperparathyroidism | en_US |
| dc.title | Enantioselective synthesis of hyperparathyroidism agent Cinacalcet hydrochloride | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC Vol.61(05) [May 2022] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJC 61(5) 503-507.pdf | Main Article | 3.65 MB | Adobe PDF | View/Open |
| IJC 61(5) 503-507 Suppl. Data.pdf | Supplementary Data | 301.21 kB | Adobe PDF | View/Open |
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