Application of diacetoxyiodobenzene in the desulfurization of arylthioureas

Abstract

In the present study, the utility of the hypervalent iodine(III) reagent, diacetoxyiodobenzene is extended for the efficient synthesis of variously substituted aryl cyanamides. The reaction presents efficient conversion of thioureas to cyanamides under the conditions of ambient temperature while stirring. This organoiodine(III) mediated method features easy isolation of the products and represents an excellent example illustrating thiophilic property of diacetoxyiodobenzene in the desulfurization of thioureas.