Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/60300
metadata.dc.identifier.doi: https://doi.org/10.56042/ijc.v61i8.65044
Title: Synthesis of bioactive chlorinated 10H-phenothiazines, sulfones, ribofuranosides and their antimicrobial activity
Authors: Goyal, Arun
Agarwal, Shikha
Gautam, D C
Keywords: Phenothiazine;Smiles rearrangement;Sulfones;Antimicrobial properties;Ribofuranosides
Issue Date: Aug-2022
Publisher: NIScPR-CSIR,India
Abstract: This article reports synthesis of some new prospective bioactive 10H-phenothiazines, their sulfones and ribofuranosides that have shown significant antimicrobial activity against some selected strains of fungi, gram positive and gram negative bacteria and leads us to develop a possibly potent class of antimicrobial agents. 10H-phenothiazines are prepared via Smiles rearrangement. Their sulfones and ribofuranosides are prepared by oxidation with 30% hydrogen peroxide in glacial acetic acid and reaction with -D-ribofuranose-1-acetate-2,3,5-tribenzoate (sugar), respectively.
Page(s): 842-848
ISSN: 2583-1321 (Online); 0019-5103 (Print)
Appears in Collections:IJC Vol.61(08) [August 2022]

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