Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/60720| metadata.dc.identifier.doi: | https://doi.org/10.56042/ijc.v61i10.59435 |
| Title: | One-pot Michael addition and cyclo-elimination cascade synthesis of thiazolo-[4,5-b]pyridin-6-carbonitrile scaffold |
| Authors: | Tiwari, Shailendra Singh, Vishal Kumar Rahmani, Shahla Ahmad, Akeel Begum, Kahkashan |
| Keywords: | 3-Benzyl-4-thiazolidinon-2-thione;Carbonitrile;Antibacterial;antifungal activity |
| Issue Date: | Oct-2022 |
| Publisher: | NIScPR-CSIR,India |
| Abstract: | A series of thiazolo [4,5-b]- pyridine-6-carbonitriles scaffold have been synthesized conveniently and smoothly in a single step in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3d, 3e, 3f, 4c, 4d, 4e and 4f have shown good antibacterial as well as antifungal activity. |
| Page(s): | 1097-1102 |
| ISSN: | 2583-1321 (Online); 0019-5103 (Print) |
| Appears in Collections: | IJC Vol.61(10) [Oct 2022] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJC 61(10) 1097-1102.pdf | 729.09 kB | Adobe PDF | View/Open |
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