Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/60829
metadata.dc.identifier.doi: https://doi.org/10.56042/ijc.v61i11.63897
Title: One pot synthesis of 4,5-dibromo-3,6-diarylpyridazine from 1,4-diarylbuta- 1,3-diyne
Authors: Shit, Prasenjit
Singha, Raju
Keywords: Diyne;NBS;Cyclization;One pot reaction;Pyridazine
Issue Date: Nov-2022
Publisher: NIScPR-CSIR, India
Abstract: A one-pot two-step methodology has been developed for the synthesis of 4,5-dibromo-3,6-diarylpyridazines starting from easily available starting material 1,4-diarylbuta-1,3-diynes. The reaction goes through the electrophilic addition of Br+ ion with alkyne bonds followed by nucleophilic addition of hydrazine and intramolecular cyclization.
Page(s): 1159-1163
ISSN: 2583-1321 (Online); 0019-5103 (Print)
Appears in Collections:IJC Vol.61(11) [Nov 2022]

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