Synthesis of pyrazolines promoted by Amberlyst-15 catalyst

Abstract

The condensation of a series of aromatic ketones with aromatic aldehydes under aldol conditions affords 1-aryl-3-(substituted­phenyl/phenyl furanyl/thienyl)-2-propen-1-ones <b style="">1</b>. The resulting propenones undergo facile and clean cyclization with hydrazine and substituted hydrazine derivatives to yield 3-aryl-5-(substituted­phenyl/phenylfuranyl/thienyl)-2-pyrazolines <b style="">2</b>.<b style=""> </b>This reaction is carried out in the presence of Amberlyst–15 catalyst to afford the above pyrazolines <b style="">2</b> in considerably good yield. All the synthesized compounds have been characterized by spectral studies.