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http://nopr.niscpr.res.in/handle/123456789/6225| Title: | Propionic acids in organic synthesis: Novel synthesis of benzimidazole, 3,1-benzoxazine, 3-aminoquinazoline and 3-aminothieno[2,3-d]pyrimidine derivatives containing 2-naphthyl propionyl moiety |
| Authors: | Al-Sehemi, Abdullah G M El-Sharief, A M Sh Ammar, Y A |
| Keywords: | Propionic acids;benzimidazole;benzoxazine;aminoquinazoline;aminothieno pyrimidine;naphthyl propionyl moiety;ammonium thiocyanate;sodium azide |
| Issue Date: | Feb-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D |
| Abstract: | Naproxenoyl chloride 2 is reacted with some nucleophilic reagents as ammonium thiocyanate and sodium azide to produce the novel isothiocyanate 3 and azide 4 derivatives, respectively. Interaction of isothiocyanate 3 with 1,2-phenylenediamine and anthranilic acid has produced the corresponding benzimidazole 5 and 3,1-benzoxazine 7 derivatives, respectively. Treatment of acid azide 4 with p-toluidine afforded urea derivative 9. The novel quinazolinone 11 was synthesized by acylation of methyl anthranilate with acid chloride 2 followed by treatment with hydrazine hydrate. |
| Page(s): | 450-455 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(02) [February 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(2) 450-455.pdf | 127.01 kB | Adobe PDF | View/Open |
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