Use of polyfunctionalized ethylene synthons: Convenient synthesis of biologically active trifluoromethyl containing N-substituted<b style="">-</b>benzoylpyrazoles and triazole

Abstract

Ten biologically active trifluoromethyl containing N-substituted-benzoylpyrazoles (<b>3a-d</b>, <b>4a-d</b>, and <b>6a, b</b>) and one triazole analogue <b>5</b> have been conveniently synthesized from four versatile polyfunctionalized ethylene synthons and one novel synthon N-cyanoimido-S,S- dimethyldithio-carbonate (CIDT, <b>v</b>), respectively. The reactions of trifluoromethyl containing substituted benzoylhydrazine with classical synthons such as ethyl dimethylaminomethylene- malonate, acetylacetone and ethyl acetoacetate have also been investigated. Herbicidal, fungicidal and plant-growth regulation activities for all reported new compounds have been determined and reported.