Pharmacognosy and biological activity of <i style="">Cordia rothii</i> Roem. & Schult. bark

Abstract

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<i style="">Cordia rothii </i>Roem. &amp; Schult. bark has reputation of being effective in heart ailments in Saurashtra region of Gujarat. The investigation was undertaken to study the microscopy, chemical constituents and pharmacological actions of <i style="">Cordia rothii</i> Roem. &amp; Schult. bark. Phytochemical analysis of different bark extracts revealed the presence of alkaloids, glycoalkaloids, coumarins and inorganic salts. The aqueous extract of the bark was found to produce significant increase in force of contraction along with chronotropic effects on isolated rat heart preparations. The same extract did not show increase in urine output, however a significant increase in sodium as well as potassium excretion was noticed. Alcoholic extract was found to decrease glucose levels as compared to control. The study corroborates the cardiotonic activity attributed to <i style="">Cordia rothii</i> bark.

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