Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/62900| metadata.dc.identifier.doi: | https://doi.org/10.56042/ijc.v62i11.5015 |
| Title: | A highly efficient route for synthesis of N-hydroxymethyl sumatriptan and sumatriptan dimer: Impurity C and H of anti-migraine drug sumatriptan |
| Authors: | Suryawanshi, M R Rane, R A Babhulkar, G V Khobragade, P D Moharir, S R Chindhe, S A Pawar, D K |
| Keywords: | Impurities;HPLC;NMR;Migraine |
| Issue Date: | Nov-2023 |
| Publisher: | NIScPR-CSIR,India |
| Abstract: | This research work describes a highly efficient route for the synthesis and characterization of the two potential sumatriptan impurities, N-hydroxymethyl sumatriptan (Impurity C) and sumatriptan dimer (Impurity H). The purity of the synthesized impurities have been confirmed using HPLC, and their structures have been identified by using MS and ¹H NMR spectroscopy. |
| Page(s): | 1201-1207 |
| ISSN: | 2583-1321 (Online); 0019-5103 (Print) |
| Appears in Collections: | IJC Vol.62(11) [November 2023] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJC 62(11) 1201-1207.pdf | 745.8 kB | Adobe PDF | View/Open | |
| IJC 62(11) 1201-1207_Suppl. Data.pdf | 1.11 MB | Adobe PDF | View/Open |
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