Development and Verification of Electrokinetic Injection Logical Control Mode in Microfluidic Device

Abstract

This study presents a methodology for discretely injecting sample flows propelled by electroosmosis within a microfluidic device. The inquiry begins by analyzing the buffer distance required to hinder diffusion between successive distinct sample entities. Following this, a systematic formulation is developed to identify operational parameters that ensure the comprehensive deposition of the specimen segment into the assigned discharge reservoir. The results indicate that precise manipulation of voltages applied to the microfluidic device's various inlet and outlet channels enables the automatic and continuous delivery of samples with varying lengths to specified outlet reservoirs. Experimental evidence supports the claim that applying a voltage to the non-receiving reservoir during injection enhances the microfluidic device's injection performance by preventing sample leakage. Furthermore, findings from both experimental and numerical analyses suggest that optimizing the spatial configuration of the outlet channels enhances the overall efficiency of the injection process.