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http://nopr.niscpr.res.in/handle/123456789/6443| Title: | Calcium chloride catalyzed three component, one-pot condensation reaction: An efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones |
| Authors: | Gangadasu, B Narender, P Raju, B China Rao, V Jayathirtha |
| Keywords: | Biginelli reaction;dihydropyrimidinones;calcium chloride;economical and ecofriendly |
| Issue Date: | May-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C 07 D |
| Abstract: | CaCl2 is an efficient, inexpensive and readily available catalyst for the three component, one-pot condensation reaction of an aldehyde, -ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yield. This method provides an envirofriendly, easy workup and isolation process. |
| Page(s): | 1259-1263 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(05) [May 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(5) 1259-1263.pdf | 115.9 kB | Adobe PDF | View/Open |
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-ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yield. This method provides an envirofriendly, easy workup and isolation process.