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http://nopr.niscpr.res.in/handle/123456789/6447| Title: | Synthesis and antibacterial screening of N-[Naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl] spiroindoloazetidin-2-ones/thiazolidin-4-ones |
| Authors: | Suryavanshi, Jitendra P Pai, Nandini R |
| Keywords: | Naphthopyrans;azetidin-2-ones;thiazolidin-4-ones;2-oxo-1H-indole;antibacterial activity |
| Issue Date: | May-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C 07 D |
| Abstract: | 2-Amino-11-hydronaphtho[2,1:5,6]pyrano[4,3-d]thiazole 1a-d on treatment with isatin affords naphtho[1,2-b]pyrano[3,4-d]thiazolo-8-yl(3-imino-2-oxo-1H-indole 2a-d which on further reaction with chloroacetyl chloride and mercaptoacetic acid yields the corresponding N-[naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl]spiro-[3H-indole-(1H,2H)-3,4-(2H)-3-chloroazetidin-2,2-diones 3a-d and N-[naphtho[1,2-b]pyrano[3,4-d]thiazol-8-yl]spiro-[3H-indole-(1H,2H)-3,2-(4H)-thiazolidine]-2,4-dione 4a-d. All the compounds 2a-d, 3a-d and 4a-d have been screened and found to possess considerable antibacterial activity. |
| Page(s): | 1227-1230 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(05) [May 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(5) 1227-1230.pdf | 45.83 kB | Adobe PDF | View/Open |
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