Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/645| Title: | Synthesis of some 1,3,4-oxadiazole derivatives as potential anti-inflammatory agents |
| Authors: | Amir, Mohd Javed, S A Kumar, Harish |
| Keywords: | 1,3,4-Oxadiazoles;1,2,4-Triazine-5-one;Anti-inflammatory;Ulcerogenicity;Lipid peroxidation;Ibuprofen |
| Issue Date: | Jun-2007 |
| Publisher: | CSIR |
| Abstract: | The synthesis of some new 1,3,4-oxadiazole derivatives and 1,2,4-triazine-5-one has been described. IR, ¹H NMR and mass spectral data support the structures of newly synthesized compounds. All the compounds have been tested in vivo for their anti-inflammatory activity by carrageenin-induced rat paw edema method. The compounds, which show good anti-inflammatory activity, have been screened for their ulcerogenic and lipid peroxidation activities. |
| Page(s): | 1014-1019 |
| ISSN: | 0376-4699 |
| Appears in Collections: | IJC-B Vol.46B(06) [June 2007] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 46B(6) (2007) 1014-1019.pdf | 119.96 kB | Adobe PDF | View/Open |
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