Green biosynthesis, characterization, and anticancer activity of Sargassum cinctum zinc nanoparticles

Abstract

This work aims at exploring the green synthesis of ZnO NPs from Sargassum cinctum; a brown marine macro algae. In the green synthesis of ZnO NPs, the bioactives present in Sargassum cinctum extract are capable of reducing and stabilising agents in the development of the said particles. In contrast to normal approaches, which usually involve the use of harmful chemicals to make nanoparticles, this technique is considered ecologically beneficial. X-ray diffraction, scanning electron microscopy, and fourier transform infrared spectroscopy studies were employed to characterise the synthesised Sc-ZnO NPs. The crystalline structure, size distribution, and functional groups revealed in the seaweed extract were all supported by these studies and may be the reason for the nanoparticles stability and biological activity. In order to determine the anticancer property of the Sc-ZnO NPs, the particles were tested on breast cancer cell lines. The findings shown in the outcomes showed that Sc-ZnO NPs had the ability to suppress the growth of breast cancer cells. In general, this research indicates that Sc-ZnO NPs prepared with the help of green techniques based on Sargassum cinctum might be considered as a rather effective and environmentally friendly anticancer agent for breast cancer. The observations made allow for the possibility of the further use of these nanoparticles for the creation of new, environmentally-friendly anticancer agents that have less adverse effects on the environment and high selectivity towards cancer cells.