Schiff base ligand and metal (II) complex: Synthesis, characterization and biological evaluation

Abstract

Mixed ligand complexes of Cu (II), Ni (II), Mg (II), Hg (II) and Fe (II) with an innovative Schiff base ligand denoted as (L1), (Z)-2-(1-hydrazineylideneethyl)-3H-benzo[f]chromen-3-one and (L2), (E)-2-(1-(2-phenylhydrazineylidene)ethyl)-3H-benzo[f]chromen-3-one, as the principal ligands have been synthesized and characterized. Assessments include elemental analyses and mass spectrometry, Fourier transform-infrared and ultraviolet-visible spectroscopy. The mixed ligand complex has been evaluated for its antibacterial activity against two Gram-positive bacteria (Bacillus subtilis, MTCC 441 and Staphylococcus aureus, MTCC 96) and two Gram-negative bacteria (Pseudomonas aeruginosa, MTCC 1866 and Escherichia coli, MTCC 443).