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http://nopr.niscpr.res.in/handle/123456789/661| Title: | Synthesis and evaluation of some 1, 4-dihydropyridine and their derivatives as antihypertensive agents |
| Authors: | Pattan, Shashikant R Rasal, V P VVenkatramana, N Khade, A B Butle, S R Jadhav, S G Desai, B G Manvi, F V |
| Keywords: | Antihypertensive;Vasodilators;Antidiabetic;Antitumour;Antimicrobial |
| Issue Date: | Apr-2007 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl. ⁸ C07D |
| Abstract: | A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-2-hydroxy propoxy]-phenyl}-pyridine-3, 5-carbamoyl have been synthesized and the structure of the compounds have been confirmed by IR, ¹H NMR , MS & elemental analysis. The title compounds have been evaluated for antihypertensive activity by tail-cuff method. Some of these compounds have been found to exhibit excellent antihypertensive activity. |
| Page(s): | 698-701 |
| ISSN: | 0376-4699 |
| Appears in Collections: | IJC-B Vol.46B(04) [April 2007] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 46B(4) (2007) 698-701.pdf | 102.96 kB | Adobe PDF | View/Open |
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