Synthesis, characterization and biological studies of some triazolothiadiazines and triazolothiadiazoles containing 6-chloropyridin-3-yl methyl moiety

Abstract

4-Amino-5-(6-chloropyridin-3-yl methyl)-4<i style="">H</i>-1,2,4-triazole-3-thiol has been synthesized and was converted into 3-(6-chloropyridin-3-yl methyl)-6-(4-substituted-phenyl)-7<i style="">H</i>-1,2,4-triazolo[3,4-<i style="">b</i>]-1,3,4-thiadiazines and<b style=""> </b>(6-chloropyridin-3-yl­methyl)-6-(4-substituted-phenyl)-7<i style="">H</i>-1,2,4-triazolo[3,4-<i style="">b</i>]-1,3,4-thiadiazoles. The newly synthesized compounds are characterized on the basis of elemental analysis, IR, ¹H NMR and mass spectral data. Some of the compounds are screened for their antibacterial and insecticidal activities.