Synthesis of α-hydroxy, β-bromo-exo-dicyclopentadiene-1-one: A new building block for cyclopentanoids

Abstract

Herein, we described a simple synthetic strategy for the preparation of α-hydroxy, β-bromo-exo-dicyclopentadiene-1-one by following a three-step sequence. The synthetic strategy relies on operationally simple reactions and high yielding steps. The newly synthesized compounds have been characterized by NMR. As the disclosed compound α-hydroxy, β-bromo-exodicyclopentadiene- 1-one is highly functionalized but structurally similar to exo-dicyclopentadiene-1-one and it can be used a key building block for expanding the chemical space of cyclopentanoid derivatives.