Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/6765| Title: | Synthesis and biological evaluation of ureido derivatives as VLA-4 antagonists |
| Authors: | Sattigeri, Viswajanani J Soni, Ajay Gupta, Lavleen K Ray, Abhijit Ahmad, Sharif Gupta, Jang B Salman, Mohammad |
| Keywords: | VLA-4 antagonists;bioisosteres;ureido derivatives |
| Issue Date: | Nov-2006 |
| Publisher: | CSIR |
| IPC Code: | Int. Cl.8 C07D |
| Abstract: | Bioisosteric replacement based design strategy was employed in order to improve pharmacokinetic properties of TBC-3486, a potent VLA-4 antagonist. However, the newly synthesized analogs did not show any significant activity. |
| Page(s): | 2534-2541 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(11) [November 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(11) 2534-2541.pdf | 82.23 kB | Adobe PDF | View/Open |
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