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http://nopr.niscpr.res.in/handle/123456789/6779Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sharma, S D | - |
| dc.contributor.author | Bhaduri, Susmita | - |
| dc.contributor.author | Kaur, Gurpreet | - |
| dc.date.accessioned | 2009-12-09T11:05:47Z | - |
| dc.date.available | 2009-12-09T11:05:47Z | - |
| dc.date.issued | 2006-12 | - |
| dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/6779 | - |
| dc.description | 2710-2715 | en_US |
| dc.description.abstract | L-Tryptophan methyl ester hydrochloride 2 undergoes Pictet-Spengler reaction with aromatic aldehydes in non-acidic aprotic media to furnish tetrahydro- -carbolines. The reaction proceeds in good yield and excellent diastereoselectivity giving cis isomers 4a-c and 6a as the major product. Use of an optically active aldehyde 10 for this reaction yields enantiopure cis-1,3-disubstituted 1,2,3,4-tetrahydro--carboline 11. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | CSIR | en_US |
| dc.relation.ispartofseries | Int.Cl.8 C07D | en_US |
| dc.source | IJC-B Vol.45B(12) December 2006] | en_US |
| dc.subject | Pictet-Spengler reaction | en_US |
| dc.subject | -carbolines | en_US |
| dc.subject | diastereoselection | en_US |
| dc.subject | asymmetric synthesis | en_US |
| dc.subject | enantiopure | en_US |
| dc.title | Diastereoselective synthesis of 1,3-disubstituted 1,2,3,4 tetrahydro--carbolines using Pictet-Spengler reaction in non-acidic aprotic media | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-B Vol.45B(12) December 2006] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(12) 2710-2715.pdf | 56.37 kB | Adobe PDF | View/Open |
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