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http://nopr.niscpr.res.in/handle/123456789/6783| Title: | Synthesis, antibacterial and antifungal activity of some new pyrido quinazolones |
| Authors: | Singh, V K Pandey, V K |
| Keywords: | Tetrahydroquinazolines;calcium antagonists;alkyli-deno/aryldeno-bis-ureas;antibacterial;antifungal |
| Issue Date: | Dec-2006 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.8 C07D |
| Abstract: | Alkylideno/arylideno bis ureas 1 synthesized by ureidoalkylation in the presence of alcohols–which on treatment with p-aminobenzoic acid results in 4-aryl-6-carboxylato-1,2,3,4-tetrahydroquinazolines 2. Reaction of 2 with benzoin in presence of polyphosphoric acid yields 4-aryl-8,9-diphenyl-1,4 dihydro-3H, 7-oxo-1,3-diaza anthracene-2,6-dione 3. Condensation of 3 with aromatic primary amine affords N-aryl-8,9-diphenyl (-2-oxo-pyrido [g]-4-aryl-2-oxo-1,3-dihydro quinazolines 4. The new compound 4 has been screened for their antibacterial and antifungal activities. |
| Page(s): | 2745-2748 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.45B(12) December 2006] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 45B(12) 2745-2748.pdf | 44.9 kB | Adobe PDF | View/Open |
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