Evaluation of anti-inflammatory activity of the pods of Iklil-ul-Malik (<i>Astragalus hamosus</i> Linn.)

Abstract

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The effect of test drug <i style="">Iklil-ul-Malik </i>(<i style="">Astragalus hamosus</i> Linn.) was studied in healthy adult Wistar rats of either sex weighing 150-200 g; animals were divided into 4 groups of 6 animals each. Animals in Group I served as control and was administered with 2 ml/kg distilled water. In Group II standard drug Piroxicam was given in the dose of 2.8 mg/kg. Animals in Group III and IV were treated with the dose of 0.58 g/kg of aqueous and alcoholic extract of <i style="">Iklil-ul-Malik</i>, respectively. Inflammation was induced by Carrageenin injection in rat hind paw. The significant reduction (<i>P</i><0.01) was observed after 3 hours of injection. The percentage inhibition in standard and test groups was found to be 59.43, 52.17 and 54.34 %, respectively.<b></b>

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