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http://nopr.niscpr.res.in/handle/123456789/8755| Title: | A facile synthesis of carvedilol, β-adrenergic blocking agent, via a key 5-substituted-2-oxazolidinone intermediate |
| Authors: | Madhusudhan, G Kumar, B Anand Chintamani, U S Rao, M Narasimha Udaykiran, D Suresh, T Kumar, V Kiran Mukkanti, K |
| Keywords: | Carvedilol;5-substituted-2-oxazolidinone;impurity B;β-adrenergic blocking agent;β-amino alcohol |
| Issue Date: | May-2010 |
| Publisher: | CSIR |
| Abstract: | A facile synthesis of Carvedilol via a key 5-substituted-2-oxazolidinone intermediate is described and this approach avoids the formation of bis side product (impurity B). This approach could be useful for the preparation of many β-amino alcohols without formation of bis impurity. |
| Page(s): | 606-610 |
| Appears in Collections: | IJC-B Vol.49B(05) [May 2010] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 49B(5) 606-610.pdf | 149.2 kB | Adobe PDF | View/Open |
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