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http://nopr.niscpr.res.in/handle/123456789/8941| Title: | Synthesis of syn-N-aryl sulfonyl-4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates and their conversion to ant-form using DBU |
| Authors: | Madhusudhan, G Reddy, G Om Ramanatham, J Dubey, P K |
| Issue Date: | Feb-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 263/00 // A 61 P 31/04 |
| Abstract: | Novel syn-N-arylsulfonyl-4-substituted
phenyl-2-oxo-1,3-oxazolidine-5-carboxylates have been synthesized from the
corresponding  -azido alcohols and converted to their anti-form
by epimerizing C-2 proton using DBU. Studies on the stabilization energies are
done to evaluate conversion from syn-to anti-and not the
vice-versa. All the compounds have been tested for their in vitro anti-bacterial
activity against S. aureus, E. faecalis and E. faecium. |
| Page(s): | 366-371 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.44B(02) [February 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(2) 366-371.pdf | 119.51 kB | Adobe PDF | View/Open |
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