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http://nopr.niscpr.res.in/handle/123456789/8968Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mereyala, Hari Babu | - |
| dc.contributor.author | Sambaru, Kalyani | - |
| dc.date.accessioned | 2010-05-14T11:30:47Z | - |
| dc.date.available | 2010-05-14T11:30:47Z | - |
| dc.date.issued | 2005-03 | - |
| dc.identifier.issn | 0975-0983(Online); 0376-4699(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/8968 | - |
| dc.description | 615-617 | en_US |
| dc.description.abstract | A new method for the synthesis of bisacodyl 1 is described. The key step involves migration of 2-pyridacyl group of phenyl pyridine-2-carboxylate 4 in AlCl3 at 160 oC to yield the intermediate 4-hydroxyphenyl (2-pyridyl) ketone 5a. The reaction of 5a with phenol using H3PO4 gives 1. This method has advantage over the existing literature methods because easily available pyridine-2-carboxylic acid is used as a starting material instead of the less stable pyridine-2-carboxaldehyde. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | CSIR | en_US |
| dc.relation.ispartofseries | Int.Cl.7 C 07 C 15/14 | en_US |
| dc.source | IJC-B Vol.44B(03) [March 2005] | en_US |
| dc.title | Synthesis of triphenylmethane derivative: Bisacodyl | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-B Vol.44B(03) [March 2005] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(3) 615-617.pdf | 72.53 kB | Adobe PDF | View/Open |
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