Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/8977| Title: | Enantioselective synthesis of (S)- -arylpropionic acids via Pd-catalyzed kinetic resolution of benzylic alcohols |
| Authors: | Thakur, Vinay V Sudalai, A |
| Issue Date: | Mar-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 C 53/122 |
| Abstract: | A convenient synthetic route for the synthesis of three (S)-a-propionic acids, (S)-naproxen (90% ee), (S)-ibuprofen (82% ee) and (S)-phenylpropionic acid (92% ee) is described. Pd-catalyzed oxidative kinetic resolution of the corresponding benzylic alcohols is used as a key step to introduce stereogenicity into the molecule. |
| Page(s): | 557-562 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.44B(03) [March 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(3) 557-562.pdf | 64.15 kB | Adobe PDF | View/Open |
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