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http://nopr.niscpr.res.in/handle/123456789/8980| Title: | Synthesis of imidazole, coumarin and isoxazole containing new triheterocyclic compounds and their derivatives |
| Authors: | Rajanarendar, E Karunakar, D Srinivas, M |
| Issue Date: | Mar-2005 |
| Publisher: | CSIR |
| IPC Code: | Int.Cl.7 C 07 D 261/00, 233/54, 311/10 |
| Abstract: | Reaction of substituted 4-amino-3-methyl-5-styrylisoxazoles 1 with 3-(2-bromoacetyl)coumarin 2 in abs. ethanol leads to the formation of 3-[2-(3-methyl-5-styryl-4-ylamino)acetyl]chromen-2-ones 3, which are subsequently cyclised by treatment with KSCN to 3-[1-(3-methyl-5-styryl-isoxazol-4-yl)-2-mercapto-1H-imidazol-4-yl]-1-benzopyran-2H-ones 4. 2-Mercaptoimidazoles 4 on treatment with ClCH2COCl in DMF / abs. ethanol give unexpected product esters 5. The reaction of 4 with phenacyl bromides results in the formation of thioethers 6. |
| Page(s): | 563-567 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.44B(03) [March 2005] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 44B(3) 563-567.pdf | 52.61 kB | Adobe PDF | View/Open |
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