Wound healing potential of ethanolic extract<i style=""> </i>of<i style=""> Kalanchoe pinnata </i>Lam. leaf—A preliminary study

Abstract

The extract of <i style="">K. pinnata </i>was evaluated for its wound healing activity by<i style=""> </i>using excision wound model in rats. On day 11, animals treated with the ethanolic leaf extract exhibited 86.33 % reduction in the wound area, compared to petroleum jelly treated control (69.36%) and the mupirocin treated standard (85.49%). The hydroxyproline content of extract treated animals was higher, as compared to control and the standard groups. Histological analysis was also consistent with the proposal that <i style="">K. pinnata </i>leaf extract exhibits significant wound healing potential. The increased rate of wound contraction and hydroxyproline content in the extract treated animals supports the claims made by traditional healers of the benefits obtained from the medicinal use of <i style="">K. pinnata</i>.